Preferred Clone

Human type B1 thymoma stained with anti-TdT antibody. Note the immature T-cells are positive.

TdT

Hematopathology

ZM51 Monospecific Mouse Monoclonal

Terminal Deoxynucleotidyl Transferase (TdT) is a DNA polymerase located in the cell nucleus which catalyzes the polymerization of deoxynucleotides at the 3’hydroxyl ends of oligo or polydeoxynucleotide initiators and functions without a template. TdT is considered to be a highly specific marker for the diagnosis and classification of acute lymphoblastic lymphoma/leukemias. The determination of TdT expression is most valuable when it is different to differentiate histologically between lymphoblastic lymphoma and Burkitt’s lymphoma.

Specifications

Species Reactivity:Humans; others not tested

Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As:Buffer with protein carrier and preservative

Storage:Store at 2ºC to 8ºC

Control:Thymus

Visualization:Nuclear

Isotype:IgG1 /κ

Immunogen:Recombinant fragment (around aa 52-192) of human DNTT protein

Ordering Information

USA International

Package Inserts

IFU-TdT ZM51

Regulatory Notice

Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.

Accept Reject

SDS