Steroidogenic Factor-1 (SF-1)

    Neuropathology/Endocrine
    ZR350 Rabbit Monoclonal

    The Steroidogenic Factor 1 (SF-1) protein is a transcription factor involved in sex determination by controlling activity of genes related to the reproductive glands or gonads and adrenal glands. This protein is encoded by the NR5A1 gene, a member of the nuclear receptor subfamily, located on the long arm of chromosome 9 at position 33.3. SF-1 is expressed in the cortex of normal adrenal gland, adrenal cortical adenomas and carcinomas. It is also positive in sex-cord stromal tumors of testicle and ovarian origins.

    Specifications
    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Adrenal cortical carcinoma
    Visualization:Nuclear
    Isotype:IgG
    Immunogen:Full-length of human SF-1 protein
    Ordering Information
    Classification IVD
    Catalogue Number Z2590RL
    Classification IVD
    Catalogue Number Z2590RL
    Package Inserts
    IFU-Steroidogenic Factor-1 (SF-1) ZR350
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.
    SDS
    SDS