Gynecological Pathology
    ZR389 Rabbit Monoclonal

    Op18 (for oncoprotein 18, also designated stathmin, prosolin or metablastin) is a conserved, Tubulin-associated, intracellular phosphoprotein. Many different phosphorylated forms of Op18 are observed and expressed as two different isoforms. Op18 is a critical regulator of microtubulin dynamics and is downregulated by p53. It serves as a transducing protein via phophorylation for various cell signaling pathways and is involved in mitosis and differentiation. Op18 is present in many cancers, including breast carcinomas, and is highly expressed in acute leukemias of different subtypes.

    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Brain or squamous cell carcinoma
    Immunogen:Recombinant fragment of human STMN1 protein
    Ordering Information
    Classification IVD
    Catalogue Number Z2754RL
    Classification IVD
    Catalogue Number Z2754RL
    Package Inserts
    IFU-Stathmin ZR398
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.