General & Epithelial Markers
    ZR115 Rabbit Monoclonal

    S100P is a 95-amino-acid protein and a member of the S100 family. S100P has been shown to mediate tumor growth, metastasis, and invasion through the binding of Ca2+ ions, the receptor for advanced glycation end products, cytoskeletal protein ezrin, calcyclin-binding protein/Siah-1-interacting protein, and cathepsin D.S100P highly expressed in human placenta, gastrointestinal tract, and esophageal mucosa, but always negative in pancreas and liver. Overexpression of S100P has been detected in several cancers such as breast, colon, prostate, pancreatic, and lung carcinomas, and the protein has been functionally implicated in carcinogenic processes. S100P could serve as a diagnostic marker, prognostic/predictive indicator, and therapeutic target for different carcinomas.

    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Colon cancer
    Immunogen:Recombinant fragment corresponding to C-terminal of human S100P protein
    Ordering Information
    Classification IVD
    Catalogue Number Z2419RL
    Classification IVD
    Catalogue Number Z2419RL
    Package Inserts
    IFU-S100P ZR115
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.