preferred clone

Formalin-fixed, paraffin-embedded human neuroblastoma stained with anti-PHOX2B antibody using peroxidase-conjugate and DAB chromogen. Note nuclear staining of tumor cells

PHOX2B

Neuropathology/Endocrine

ZR292 Rabbit Monoclonal

Paired homeobox protein 2B (PHOX2B) is a transcription factor located on chromosome 4p13, which is essential for forming autonomic ganglia in the autonomic nervous system. PHOX2B is expressed in neuroblastoma, brain, and adrenal glands. PHOX2B deficiency can lead to susceptibility to congenital central hypoventilation syndrome (CCHS) and neuroblastoma type 2 (NBLST2).

Specifications

Species Reactivity:Humans; others not tested

Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As:Buffer with protein carrier and preservative

Storage:Store at 2ºC to 8ºC

Control:Neuroblastoma

Visualization:Nuclear

Isotype:IgG

Immunogen:Recombinant fragment of human PHOX2B protein

Ordering Information

USA International

Package Inserts

IFU-PHOX2B ZR292

Regulatory Notice

Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.

Accept Reject

SDS