GI Pathology
    ZR19 Rabbit Monoclonal

    Mucins are high molecular eight glycoproteins with 80% carbohydrate contents and the remaining 20% is constituted by protein core. Gastric mucin M1 antigens are detected/found in columnar mucus cells of surface gastric epithelium and in goblet cells of the fetal and precancerous colon but not in those of normal colon. Evidence from the literature suggests that they are associated with the peptide core of mucins Resurgence of gastric mucin reactivity during colonic carcinogenesis is suggested to be due to either reexpression of the peptide core of gastric (or fetal colonic) mucins in the adult colon or due to changes in the glycosylation pattern of mucin which expose the hidden M1 antigens.

    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Gastric carcinoma
    Visualization:Cell membrane
    Immunogen:Recombinant full-length human MUC5AC protein
    Ordering Information
    Classification IVD
    Catalogue Number Z2703RL
    Classification IVD
    Catalogue Number Z2703RL
    Package Inserts
    IFU-MUC-5AC ZR19
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.