General & Epithelial Markers
    CA-4001 Mouse Monoclonal

    MMPs are proteolytic enzymes capable of degrading connective tissue components. They have a common mode of activation, a conserved amino acid sequence in the putative metal binding-active site region and are inhibited by specific tissue inhibitors of metalloproteinases (TIMPs). MMPa and TIMPs play a significant role in regulating angiogenesis. MMP-2 is synthesized as a 631 amino acid proenzyme which is activated by cleavage of the first 80 amino acids. This antibody reacts with both latent and active MMP-2.

    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Placenta, bladder, breast, and ovarian carcinoma
    Isotype:IgG1 /κ
    Immunogen:A synthetic peptide derived from near N-terminal of human MMP-2 protein
    Ordering Information
    Classification IVD
    Catalogue Number Z2089ML
    Classification IVD
    Catalogue Number Z2089ML
    Package Inserts
    IFU-MMP-2 CA-4001
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.