Mammaglobin Cocktail

    Breast Pathology
    304-1A5 + ZM193 Mouse Monoclonal

    Mammaglobin is a breast-associated glycoprotein distantly related to secretoglobin family that includes human uteroglobin and lipophilin. Unlike other secretoglobin family members, mammaglobin mRNA expression is breast specific, which has been shown to be a very sensitive marker of occult breast cancer cells in sentinel lymph nodes and peripheral blood. By paraffin immunohistochemistry, the overall sensitivity of mammaglobin for breast cancers was reported about 80%. When combined with other breast-restricted markers such as GCDFP-15, an overall sensitivity of 84% could be achieved. Mammaglobin can play a contributing role in the identification of primary sites of carcinomas presenting at metastatic sites.

    Specifications
    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Normal or neoplastic breast tissue
    Visualization:Cytoplasmic
    Isotype:IgG1 /κ+IgG1 /κ
    Immunogen:Recombinant full-length of human mammaglobin protein
    Ordering Information
    Classification IVD
    Catalogue Number Z2517ML
    Classification IVD
    Catalogue Number Z2517ML
    Package Inserts
    IFU-Mammaglobin Cocktail 304-1A5 + ZM193
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.
    SDS
    SDS