Her-2/neu

    Breast Pathology
    ZR218 Rabbit Monoclonal

    Recognizes a protein of 185kDa, which is identified as c-erbB-2/HER-2/neu. Its epitope is localized in the extracellular domain. C-erbB-2/HER-2 is a member of the EGFR family. This MAb is specific and shows minimal cross-reaction with other members of the EGFR-family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain connected to a large intracellular domain by a single transmembrane sequence. c-erbB-2/HER-2 protein is over-expressed in various carcinomas, especially the breast and ovary.

    Specifications
    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Breast carcinomas
    Visualization:Cell membrane
    Isotype:IgG
    Immunogen:Recombinant protein encoding extracellular domain of human c-erbB2
    Ordering Information
    Classification IVD
    Catalogue Number Z2499RL
    Classification IVD
    Catalogue Number Z2499RL
    Package Inserts
    IFU-Her-2/neu ZR218 ASR-0
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.
    IFU-Her-2/neu ZR218 -RUO-0
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.
    SDS
    SDS