Growth Hormone

    Neuropathology/Endocrine
    ZM140 Mouse Monoclonal

    Pituitary growth hormone (GH) plays a crucial role in stimulating and controlling the growth, metabolism and differentiation of many mammalian cell types by modulating the synthesis of multiple mRNA species. These effects are mediated by the binding of GH to its membrane-bound receptor, GHR, and involve a phosphorylation cascade that results in the modulation of numerous signaling pathways. GH is synthesized by acidophilic or somatotropic cells of the anterior pituitary gland. Anti-GH is a useful marker in classification of pituitary tumors and the study of pituitary disease (acromegaly).

    Specifications
    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Pituitary
    Visualization:Cytoplasmic
    Isotype:IgG2b /κ
    Immunogen:A recombinant human Growth Hormone (GH) fragment (aa 58-187)
    Ordering Information
    Classification IVD
    Catalogue Number Z2451ML
    Classification IVD
    Catalogue Number Z2451ML
    Package Inserts
    IFU-Growth Hormone ZM140
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.
    SDS
    SDS