Preferred Clone
Human kidney stained with anti-Galectin-3 antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of tubular cells.
Galectin-3 is a member of the beta-galactosidase-binding lectin family. It is associated with cell growth, adhesion, inflammation, mRNA processing, and apoptosis. Aberrant expression of Galectin-3 is related to malignant transformation and metastasis in carcinomas of the breast, colon and thyroid. Galectin-3 reactivity can be seen in the nucleus of neutrophils, vascular endothelium, carcinomas of the colon, breast, and thyroid. Galectin-3 may be useful in the differentiation of benign and malignant thyroid neoplasms. Galectin-3 may also be useful in the identification of certain liver disorders.
Specifications
Species Reactivity:Humans; others not tested
Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Supplied As:Buffer with protein carrier and preservative
Storage:Store at 2ºC to 8ºC
Control:Papillary or follicular thyroid carcinoma
Visualization:Cytoplasmic
Isotype:IgG1 /κ
Immunogen:A synthetic peptide from the C-terminus of human LGALS3 protein (aa 150-200)
Ordering Information
Package Inserts
SDS