preferred clone
Formalin-fixed, paraffin-embedded human normal pituitary stained with anti-FSH antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of FSH secreting cells
This MAb reacts with a protein of 22kDa, identified as a beta subunit of FSH. It does not cross-react with the alpha subunit. Follicle stimulating hormone (FSH) is a hormone synthesized and secreted by gonadotrophs in the anterior pituitary gland. In the ovary, FSH stimulates the growth of immature Graafian follicles to maturation. As the follicle grows, it releases inhibin, which deactivates the FSH production. In men, FSH enhances the production of androgen-binding protein by the Sertoli cells of the testis and is critical for spermatogenesis. FSH and LH act synergistically in reproduction. FSH is a useful marker in the classification of pituitary tumors and the study of pituitary disease.
Specifications
Species Reactivity:Humans; others not tested
Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Supplied As:Buffer with protein carrier and preservative
Storage:Store at 2ºC to 8ºC
Control:Pituitary
Visualization:Cytoplasmic
Isotype:IgG
Immunogen:Recombinant full-length hFSH beta sub-unit
Ordering Information
Package Inserts
SDS