FoxP1

    Hematopathology
    EP137 Rabbit Monoclonal

    Forkhead box protein P1 (FOXP1) is a transcriptional repressor that plays an important role in the development of the brain and lung in mammals. The gene encoding this protein may act as a tumor suppressor as it is lost in several tumor types and maps to a chromosomal region (3p14.1) reported to contain a tumor suppressor gene. It is essential transcriptional regulator of B cell development. PAX5/FOXP1 translocation t(9;3) (p13;p14.1) is found in acute lymphoblastic leukemia. FOXP1 is positive in subset of diffuse large B-cell lymphoma and mucosa-associated lymphoid tissue lymphomas.

    Specifications
    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Tonsil
    Visualization:Nuclear
    Isotype:IgG
    Immunogen:Recombinant Human FOXP1 protein
    Ordering Information
    Classification IVD
    Catalogue Number Z2460RL
    Classification IVD
    Catalogue Number Z2460RL
    Package Inserts
    IFU-FoxP1 EP137
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.
    SDS
    SDS