Preferred Clone

Human tonsil stained with anti-FoxP1 antibody using peroxidase-conjugate and DAB chromogen. Note the nuclear staining of follicular and mantle B-cells.

FoxP1

Hematopathology

ZR333 Rabbit Monoclonal

Forkhead box protein P1 (FOXP1) is a transcriptional repressor. It plays an important role in the specification and differentiation of lung epithelium. Can act with CTBP1 to synergistically repress transcription but CTPBP1 is not essential. Essential transcriptional regulator of B cell development. FOXP1 protein plays an important role in the specification and differentiation of lung epithelium, also acts cooperatively with FOXP4 to regulate lung secretory epithelial cell fate and regeneration by restricting the goblet cell lineage program. FOXP1 is useful in subclassification of DLBCL and a high cutoff (≥80%) for FOXP1 is needed to achieve high specificity for the ABC subtype.

Specifications

Species Reactivity:Humans; others not tested

Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As:Buffer with protein carrier and preservative

Storage:Store at 2ºC to 8ºC

Control:Tonsil

Visualization:Nuclear

Isotype:IgG

Immunogen:Recombinant Human FOXP1 protein

Ordering Information

USA International

Package Inserts

IFU-FoxP1 ZR333

Regulatory Notice

Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.

Accept Reject

SDS