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    Factor XIIIa

    Dermatopathology
    ZM84 Mouse Monoclonal

    It recognizes a protein of 83kDa, which is identified as Factor XIIIa. It has been identified in platelets, megakaryocytes, and fibroblast-like mesenchymal or histiocytic cells in the placenta, uterus, and prostate, monocytes and macrophages and dermal dendritic cells. Anti-factor XIIIa has been found to be useful in differentiating between dermatofibroma (almost all cases are positive), dermatofibrosarcoma protuberans (-/+) and desmoplastic malignant melanoma (-). Anti-factor XIIIa positivity is also seen in capillary hemangioblastoma, hemangioendothelioma, hemangiopericytoma, xanthogranuloma, xanthoma, hepatocellular carcinoma, glomus tumor, and meningioma.

    Specifications
    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Capillary hemangioma, dermatofibroma, and placenta
    Visualization:Cytoplasmic and nuclear
    Isotype:IgG2a /κ
    Immunogen:Recombinant fragment of human Factor XIIIa protein
    Ordering Information
    Classification IVD
    Catalogue Number Z2394ML
    Classification IVD
    Catalogue Number Z2394ML
    Package Inserts
    IFU-Factor XIIIa ZM84
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.
    SDS
    SDS