Preferred Clone
Human colon adenocarcinoma stained with EP-CAM antibody using peroxidase-conjugate and DAB chromogen. Note the membranous staining of tumor cells.
EGP40 is a 40-43kDa transmembrane epithelial glycoprotein, also identified as epithelial specific antigen (ESA), or epithelial cellular adhesion molecule (Ep-CAM). It is expressed on basolateral cell surface in most simple epithelia and a vast majority of carcinomas. This antibody has been used to distinguish adenocarcinoma from pleural mesothelioma and hepatocellular carcinoma. This antibody is also useful in distinguishing serous carcinomas of the ovary from mesothelioma.
Specifications
Species Reactivity:Humans; others not tested
Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
Supplied As:Buffer with protein carrier and preservative
Storage:Store at 2ºC to 8ºC
Control:Colon carcinoma
Visualization:Cytoplasmic
Isotype:IgG2b /κ
Immunogen:Recombinant human EP-CAM protein fragment from extracellular domain
Ordering Information
Package Inserts
SDS