EGFR

    Lung/Mediastinum Pathology
    EP22 Rabbit Monoclonal

    EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGFa), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin. EGFR is overexpressed in tumors of breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium. It is predominantly present in squamous cell carcinomas.

    Specifications
    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Lung adenocarcinoma
    Visualization:Membranous
    Isotype:IgG
    Immunogen:A synthetic phospho-peptide corresponding to residues surrounding Tyr1068 of human EGF receptor
    Ordering Information
    Classification IVD
    Catalogue Number Z2037RL
    Classification IVD
    Catalogue Number Z2037RL
    Package Inserts
    IFU-EGFR EP22
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.
    SDS
    SDS