EGFR

    Lung/Mediastinum Pathology
    ZR16 Rabbit Monoclonal

    This MAb recognizes a protein of 170kDa, identified as EGFR. EGFR is type I receptor tyrosine kinase with sequence homology to erbB-1, -2, -3 -4 or HER-1, -2, -3 -4. It binds to Epidermal Growth Factor (EGF), Transforming Growth Factor-a (TGF-a), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin, and epiregulin. EGFR is overexpressed in breast, brain, bladder, lung, gastric, head & neck, esophagus, cervix, vulva, ovary, and endometrium tumors. It is predominantly present in squamous cell carcinomas.

    Specifications
    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Lung adenocarcinoma
    Visualization:Membranous
    Isotype:IgG
    Immunogen:Recombinant fragment of human EGFR protein (around aa 344-492)
    Ordering Information
    Classification IVD
    Catalogue Number Z2743RL
    Classification IVD
    Catalogue Number Z2743RL
    Package Inserts
    IFU-EGFR ZR16
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.
    SDS
    SDS