Cytokeratin 5/6

    General & Epithelial Markers
    ZM43 Mouse Monoclonal

    It recognizes polypeptides of 58kDa and 56kDa, identified as cytokeratin 5 and 6 respectively. It shows no reaction with keratin 1, 8, or 19. It stains the basal cells of squamous and glandular epithelia, part of stratum spinosum of squamous epithelium, myoepithelium, and mesothelium. It does not stain adenous epithelium. Therefore, this antibody can be used to distinguish squamous carcinoma from adenocarcinoma, and to differentiate epitheloid mesothelioma from non-epitheliod mesothelioma and adenocarcinoma. It is also a useful antibody to distinguish benign ductal hyperplasias from non-invasive neoplastic proliferations. Positive tissue: Skin.

    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Isotype:IgG1/κ& IgG2a/κ
    Immunogen:Recombinant human Cytokeratin 5 (KRT5) protein fragment (around aa 318-491); Recombinant full-length human Cytokeratin 6A (KRT6A) protein
    Ordering Information
    Classification IVD
    Catalogue Number Z2350ML
    Classification IVD
    Catalogue Number Z2350ML
    Package Inserts
    IFU-Cytokeratin 5/6 ZM43 -0-
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.