Preferred Clone

Human colon carcinoma stained with anti-keratin 18 antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of tumor glands.

Cytokeratin 18

General & Epithelial Markers

ZM205 Mouse Monoclonal

This MAb reacts with a wide variety of simple epithelia. It does not react with stratified squamous epithelia. It reacts with epithelial tumors of the gastrointestinal tract, lung, breast, pancreas, ovary, and thyroid. Cytokeratin 18, which belongs to the type A (acidic) subfamily of low molecular weight keratins, exists in combination with cytokeratin 8. It was reported that tissues from gastrointestinal tract are positive for both cytokeratin 8 and 18 but do not contain cytokeratin 14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for cytokeratin 18.

Specifications

Species Reactivity:Humans; others not tested

Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As:Buffer with protein carrier and preservative

Storage:Store at 2ºC to 8ºC

Control:Breast carcinoma

Visualization:Cytoplasmic

Isotype:IgG1 /κ

Immunogen:Recombinant human KRT18 protein

Ordering Information

USA International

Package Inserts

IFU-Cytokeratin 18 ZM205

Regulatory Notice

Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.

Accept Reject

SDS