Human thyroid gland stained with anti-keratin 18 antibody using peroxidase-conjugate and DAB chromogen. Note the cytoplasmic staining of glandular cells.

Cytokeratin 18

General & Epithelial Markers

DC10 Mouse Monoclonal

Cytokeratin 18 (CK18), which belongs to the type A (acidic) subfamily of low molecular weight keratins exists in combination with CK8. It was reported that tissues from gastrointestinal tract are positive for both CK8 and CK18 but do not contain CK14. Tissues from gastrointestinal tract, respiratory tract and urogenital tract, as well as endocrine and exocrine tissues and mesothelial cells are positive for CK18. DC10 recognizes a variety of simple epithelia including glandular epithelium but not stratified squamous epithelia.

Specifications

Species Reactivity:Humans; others not tested

Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As:Buffer with protein carrier and preservative

Storage:Store at 2ºC to 8ºC

Control:Breast carcinoma

Visualization:Cytoplasmic

Isotype:IgG1 /κ

Immunogen:Human breast cancer PMC 42 cells

Ordering Information

USA International

Package Inserts

IFU-Cytokeratin 18 DC10

Regulatory Notice

Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.

Accept Reject

SDS