UCHL-1 Mouse Monoclonal

    CD45RO (an isoform of leukocyte common antigen) is expressed on most thymocytes, monocytes, macrophages and granulocytes. It is not expressed on normal B lymphocytes. Intrathymic T cell maturation progresses from CD45RA-/CD45RO+ to CD45RA+/CD45RO-; while peripheral T cell maturation progresses from CD45RA+/CD45RO- to CD45RA-/CD45RO+. UCHL-1 reacts with mature activated T cells, most thymocytes, and a sub-population of resting T-cells within both CD4 and CD8 subsets. Shows no reactivity with normal B or natural killer cells, but reacts with granulocytes and monocytes. It rarely stains B cell lymphomas.

    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Tonsil or lymph node
    Visualization:Cell membrane
    Isotype:IgG2a /κ
    Immunogen:Interleukin-2-dependent human T lymphocytes
    Ordering Information
    Classification IVD
    Catalogue Number Z2036ML
    Classification IVD
    Catalogue Number Z2036ML
    Package Inserts
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.