CD35

    Hematopathology
    ZR58 Rabbit Monoclonal

    CD35, complement receptor 1, is a cell membrane-bound, monomeric glycoprotein on numerous cell types, including erythrocytes, leukocytes, glomerular podocytes, and follicular dendritic cells. The primary function of CD35 is to serve as the cellular receptor for C3b and C4b, the essential components of the complement system leading to clearance of foreign macromolecules. CD35 antigen is found on erythrocytes, B cells, a subset of T cells, monocytes, as well as eosinophils and neutrophils. Anti-CD35 is considered a mature B-cell marker that labels follicular dendritic reticulum cells and tumors derived from cells such as follicular dendritic cell tumor/sarcoma.

    Specifications
    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Tonsil
    Visualization:Cell membrane/surface
    Isotype:IgG
    Immunogen:Recombinant fragment (within aa650-850) of human CD35
    Ordering Information
    Classification IVD
    Catalogue Number Z2368RL
    Classification IVD
    Catalogue Number Z2368RL
    Package Inserts
    IFU-CD35 ZR587
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.
    SDS
    SDS