Ber-H2 Mouse Monoclonal

    CD30, a single chain glycoprotein, is synthesized as a 90kDa precursor which is processed in the Golgi complex into a membrane-bound phosphorylated mature 105/120kDa glycoprotein. The CD30/Ki-1 antigen is expressed by mononuclear Hodgkin and multinucleated Reed-Sternberg cells in Hodgkin’s disease, by the tumor cells of a majority of anaplastic large cell lymphomas, and by a varying proportion of activated T and B cells. Ber-H2 distinguishes large cell lymphomas derived from activated lymphoid cells from histiocytic malignancies and lymphomas derived from resting and precursor lymphoid cells or from anaplastic carcinomas. About one third of the Ki-1 positive lymphomas lack the leukocyte common antigen (CD45).

    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Hodgkin lymphoma or anaplastic large cell lymphoma
    Visualization:Cell membrane and cytoplasmic
    Isotype:IgG1 /κ
    Immunogen:Co cell line established from a patient with Hodgkin's disease of T-cell lineage
    Ordering Information
    Classification IVD
    Catalogue Number Z2101ML
    Classification IVD
    Catalogue Number Z2101ML
    Package Inserts
    IFU-CD30 Ber-H2
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.