ZM104 Mouse Monoclonal

    Recognizes a protein of 55kDa, identified as CD14 (also known as lipopolysaccharide receptor). CD14 is expressed strongly on monocytes and macrophages and weakly on the surface of neutrophils. CD14 is anchored to cells by linkage to glycosylphosphatidylinositol (GPI) and functions as a high-affinity receptor for complexes of LPS and LPS binding protein (LBP). Soluble CD14, also binding to LPS, acts at a physiological concentration as an LPS agonist and has, at higher concentrations, an LPS antagonizing effect in cell activation.

    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Tonsil or lymph node
    Visualization:Membrane and cytoplasmic
    Isotype:IgG1/ Kappa
    Immunogen:Recombinant fragment of human CD14 protein (around aa 25-148)
    Ordering Information
    Classification IVD
    Catalogue Number Z2415ML
    Classification IVD
    Catalogue Number Z2415ML
    Package Inserts
    IFU-CD14 ZM104- 0
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.