Preferred Clone

Human breast tissue stained with anti-caldesmon antibody using peroxidase-conjugate and DAB chromogen. Note cytoplasmic staining of myoepithelial cells.

Caldesmon

Soft Tissue Pathology

ZM79 Mouse Monoclonal

Caldesmon is a developmentally regulated protein involved in smooth muscle and non-muscle contraction. Two closely related variants of human caldesmon have been identified which differ in their electrophoretic mobility and cellular distribution. The h-caldesmon variant(120-150kDa) is predominantly expressed in smooth muscle whereas l-caldesmon (70-80kDa) is found in non-muscle tissue and cells. Neither of the two variants has been detected in skeletal muscle.

Specifications

Species Reactivity:Humans; others not tested

Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As:Buffer with protein carrier and preservative

Storage:Store at 2ºC to 8ºC

Control:Uterus, colon carcinoma

Visualization:Cytoplasmic

Isotype:IgG1 /κ

Immunogen:Recombinant full-length human CALD1 protein

Ordering Information

USA International

Package Inserts

IFU-Caldesmon ZM79

Regulatory Notice

Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.

Accept Reject

SDS