c-myc

    Hematopathology
    ZR355 Rabbit Monoclonal

    It recognizes a transcription factor of 64-67kDa, identified as c-myc. Its epitope spans between aa 410-419 (EQKLISEEDL) which is a specific portion of an alpha helical region of human c-myc protein. This MAb shows no cross-reaction with v-myc. c-myc is involved in the control of cell proliferation and differentiation and is amplified and/or overexpressed in a variety of tumors. Over-expression of c-myc protein occurs frequently in luminal cells of prostate intraepithelial neoplasia as well as in most primary carcinomas and metastatic disease.

    Specifications
    Species Reactivity:Humans; others not tested
    Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)
    Supplied As:Buffer with protein carrier and preservative
    Storage:Store at 2ºC to 8ºC
    Control:Burkitt lymphoma
    Visualization:Cytoplasmic and nuclear
    Isotype:IgG
    Immunogen:Recombinant fragment of human MYC protein (exact sequence is proprietary)
    Ordering Information
    Classification IVD
    Catalogue Number Z2734RL
    Classification IVD
    Catalogue Number Z2734RL
    Package Inserts
    IFU-c-myc ZR355
    Regulatory Notice
    Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.
    SDS
    SDS