Preferred Clone

Human yolk sac tumor stained with anti-AFP polyclonal antibody using peroxidase-conjugate and DAB chromogen. Note cytoplasmic staining of tumor cells..

AFP

GI Pathology

C3 Mouse Monoclonal

It recognizes an oncofetal glycoprotein with a single chain of 70kDa, which is identified as alpha-fetoprotein (AFP) (ISOBM TD-2 workshop). This MAb is highly specific to AFP and shows no cross-reaction with other oncofetal antigens or serum albumin. AFP is normally synthesized in the liver, intestinal tract, and yolk sac of the fetus. Antibody to AFP has been shown to be useful in detecting hepatocellular carcinomas (HCC) and germ cell neoplasms, especially yolk sac tumors.

Specifications

Species Reactivity:Humans; others not tested

Known Applications:Immunohistochemistry (formalin-fixed, paraffin-embedded tissues)

Supplied As:Buffer with protein carrier and preservative

Storage:Store at 2ºC to 8ºC

Control:Fetal liver or hepatocellular carcinoma

Visualization:Cytoplasmic

Isotype:IgG2a /κ

Immunogen:Alpha fetoprotein (AFP) purified from serum of a hepatoma patient

Ordering Information

USA International

Package Inserts

IFU-AFP C3

Regulatory Notice

Product classification varies based on regulations of individual countries. Please contact your local distributor for more information. Products labeled as ASR or RUO in the US might be available as IVD or RUO in respective countries.

Accept Reject

SDS